Radiological pathology of cerebrovascular disorders
January 28th, 2014 by Administrator

The author: Professor Yasser Metwally


January 28, 2014 — Neuroimaging is nothing but how "neuropathology and neuroanatomy" are approached clinically by neurologists and neurosurgeons through radiological films. Neuroimaging from the neuropathological and neuroanatomical perspectives is how gross pathology and anatomy are demonstrated radiologically. Without having a good Knowledge of neuropathology and neuroanatomy it is not possible at all to understand neuroimaging.

Neuroimaging and neuropathology share common perspectives in medicine. In no field is this more evident than in the diagnosis and study of nervous system pathology: radiology and pathology are anatomically oriented specialties that depend primarily on structural changes to diagnose disease. Both specialties are broadening their perspectives of morphology to demonstrate metabolism, as with functional imaging in radiology and with immunocytochemical markers in anatomical pathology. Pathologists thus regard their radiologic counterparts as colleagues with similar morphologic approaches to diagnosis, despite the different tools used. In no discipline is this companionship more strongly felt than in the respective subspecialties that focus on disorders of the nervous system.

Neuropathologists understand, acknowledge, and admire the numerous contributions by neuroimaging in defining many neurological disorders. Neuroimaging enable us to diagnose gross pathology during life. Neuropathologists usually must wait until autopsy to demonstrate tissue changes, but surgical specimens are becoming increasingly more frequent, for example, with the advent of epilepsy surgery.

Neuroradiologists and neuropathologists have a mutual need for collaboration. Radiologists need tissue confirmation to fully understand the significance of images seen, and pathologists’ findings need to be relevant to diagnoses that often rest initially with the neurologist/neuroradiologist, and provide insight into pathogenesis through unique tissue examinations.

In my opinion the best neuroradiologist is the neurologist or the neurosurgeons who must be capable of independently interpreting a neuroimaging study. Understanding neuropathology and neuroanatomy, and how they are demonstrated radiologically, are essential for interpreting a neuroimaging study. This EBook is directed primarily to neurologists and neurosurgeons. In this PDF publication, neuroimaging of cerebrovascular disorders is approached from the neuropathological and neuroanatomical perspectives. This publication addresses the question of how neuropathology and neuroanatomy are related to neuroimaging and why they are essential for our basic understanding of a neuroimaging study.

This publication covers cerebrovascular disorders from the radiological pathology point of view. The publication is free of charge and can be freely distributed. I certainly hope that you will find this publication as useful as I truly wish. The publication is composed of 316 pages and can be printed in high quality.

Click to download publication in PDF format (9 MB)

Click to download publication in PDF format (9 MB)


  1. Metwally, MYM: Textbook of neuroimaging, A CD-ROM publication, (Metwally, MYM editor) corporation, version 15.1 January 2014 [Click to have a look at the home page]


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